The Ministry of Science, Technology and Innovation (MOSTI) has recently launched the MyGenom project. It is a joint venture with the Ministry of Health (MOH), with goals to sequence the Malaysian genome, create a reference genome, and understand genetic variation across the country’s diverse ethnicities.
For the uninitiated, genome sequencing is the process of determining the precise order of nucleotides in a DNA molecule, which encodes genetic information about the body. This process offers insights into how individual genes function and their impact on human health.
The project, led by the Malaysia Genome & Vaccine Institute (MGVI) and the Institute for Medical Research (IMR), aims to support precision medicine by tailoring treatments to Malaysia’s unique genetic profile. According to MOSTI, MyGenom will help identify disease risks, improve treatment outcomes, and reduce healthcare burdens by using genetic data.
Apart from those mentioned, also contributing to the project are researchers from the Malaysian National Institute of Biotechnology and the National Institute of Health. This cross-agency cooperation ensures a comprehensive approach to advancing genomics and precision medicine in Malaysia.
In its first phase, MyGenom plans to sequence 2,500 genomes by 2025, with the ultimate goal of sequencing 10,000 genomes to establish accurate genetic references for Malaysia. MOSTI adds that the project team from KKM will employ three sampling strategies: continuous sampling at seven blood donation centres in selected hospitals nationwide, periodic sampling at three blood donation centres in selected hospitals, and targeted community sampling.
